Selection criteria may be adjusted at the request of the customer depending on the intended use of the product and the customer’s requirements, provided that subject safety requirements are met. At the customer’s request, subjects with a history of travel or medication ingestion that would preclude them from providing a blood product suitable for transfusion may provide granulocytes for non-clinical and non-injectable uses.

We also offer qualification samples on potential subjects to allow the end-user to determine suitability for targeted materials. Specific subjects may be requested for product collection. Subjects may donate as often as once a month and up to 12 times in any 12-month period.

Subjects are prescreened for evidence of transmissible infectious diseases with the standard panel of tests used to screen blood products for transfusion acceptability. This panel of tests is usually repeated with each collected product.

Products are collected on the COBE^® Spectra collection system.

Specific subjects may be selected from our database based on:

• Blood type
• Gender
• Ethnicity
• Human Neutrophile Antigen genotype
• Human Leukocyte Antigen phenotype

Optional pre-collection qualification screening is available:

• Total white cell count, neutrophile count, and/or other cell counts
• Recent medication usage

Optional post-collection release screening is available:

• Total nucleated white cell yield
• Neutrophile yield

Packaging and Shipment

In alignment with the intended use of the product and the customer’s requirements, granulocytaphereses can be packaged and shipped on the date of collection for overnight delivery.

Products are packaged in a manner that ensures maintenance of a temperature between 20°C and 24°C during shipment, unless an alternative method is specified by the customer. Lifeblood Biological Services uses the Golden Hour^® Platelet Shipper for shipment of these products, unless an alternative method is specified by the customer.

Continuous temperature monitoring data tracking devices are available for use at the customer’s request.

Historical Product Characteristics
Neutrophile Yield:

• Mean: TBD
• Median: TBD
• Range: TBD